Evaluation revealed that conolidine and cannabidiol drastically blocked Cav2.two channels. While in the peripheral and central anxious system, Cav2.2 channels can be found predominantly at presynaptic terminals32 and Participate in vital roles in pain perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that influence presynaptic Cav2.2 channel ac... https://stevea161xhg8.life-wiki.com/user