Epidural clonidine applied as an adjunct to community anesthetics has three distinct mechanisms of motion. Initially, the stimulation of alpha-2-receptors in the dorsal horn minimizes agony transmission. Secondly, clonidine can cause neighborhood vasoconstriction that limits vascular elimination of regional epidural anesthetics. Intense Allergic Reactions. Clonidine may cause allergic... https://www.proleviate.com/post/the-new-pain-killer-conolidine