Study into conolidine has led to discovery of an opioid receptor in your body identified as ACKR3/CXCR7. ACKR3 appears to be one of the most wanted focus on for conolidine, which also disregards another four classical opioid receptors(three). Presented the mechanism of motion of conolidine as opposed to opioids https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers